The storied Pulsar 220F powerplant is shared by the Bajaj Avenger 220 Cruise. The engine, which has a fuel-injection system, generates 19.03PS and 17.55Nm. The Avenger 220 Cruise has a five-speed transmission.

The Avenger 220 Cruise is built on solid, uncomplicated principles. The Avenger 220's suspension consists of twin rear shocks and a traditional telescopic front fork. The BS6 Avenger 220 Cruise now boasts larger 280mm front rotors as part of its updated braking system. The 130mm rear drum brake is still in place. ABS with a single channel is the default. Both ends of the Avenger's wheels have spokes.

The Avenger bike family as a whole uses the same design language, and the Bajaj Avenger 220 Cruise is no exception. Due to the fact that this is the Cruise model, it has a sizable windscreen, several chrome accents, and spoked wheels. The Avenger 220 Cruise receives a completely digital instrument cluster with an odometer, trip meter, clock, fuel gauge, and service due reminder in contrast to its smaller Avenger 160 sister. A few warning lights are included on the tank's panel.